1000mg in my system (1 met when I wake up, and 1 before lunch) before I've eaten anything. I eat lunch at around 12:00 (lo-carb, of course! ). tubolard ยท Well-Known Member 575 5 38 The advice on the packet is to take it with food to reduce the side effects, having said that I take my breakfast and evening meal metformin anything up to an hour before I actually eat. I say this with particular pleasure - I no longer take a lunchtime metformin - but when I did, it was with the first bite. I can't say that I've noticed any difference in readings no matter when I take the metformin, but have to say that I thought that food would interfere with absorption of the metformin - so have always taken it either very early in the meal or before eating. Regards, Tubs. Jay3109 94 0 26 I take my Glucophage (slow release) metformin in the morning and I too don't eat breakfast or lunch. As this form of metformin doesn't have the same nasty side effects as the ordinary sort I suspect it doesn't really matter but I believe that most people are told to take it with food.
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